Figure 6.
Effects of decreased TIP30 expression on human lung adenocarcinoma. (a–b) Correlation of TIP30 mRNA expression with OS and PPS of lung adenocarcinoma patients. Kaplan-Meier analysis was used to assess survival of stage I/II lung cancer patients from the NCI’s caArray database. (c) Growth curves of shRNA-CON and TIP30-SH1 cells treated with or without gefitinib. Cells were exposed to 10 µM gefitinib for indicating times. (d) Growth curves of shRNA-CON and Tip30-SH1 cells treated with or without U0126. Cells were exposed to 500nM U0126 for indicating times. Data were mean ± SEM of three independent experiments.