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. 2012 Sep 14;63(3):245–252. doi: 10.4097/kjae.2012.63.3.245

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Copyright © the Korean Society of Anesthesiologists, 2012

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 3 — Representative tracings of arterial blood pressure (ABP), cerebral blood flow velocity (CBFV) and beat-to-beat data of cerebrovascular resistance index (CVRi) during thigh cuff release in one subject. CVRi is shown in normalized units relative to control prerelease values obtained during -4 to 0 s. The thigh cuffs were released at time 0. The straight line through the CVRi curve (bottom graph) was determined by regression analysis of data in interval from 1 to 3.5 s after thigh cuff release and the slope of this regression line was used to calculate the rate of regulation. Melatonin did not affect CVRi or percentage restoration of CBFV before and 60 min after melatonin ingestion.