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Effects of rauwolscine on dexmedetomidine-induced concentration-response curves in endothelium-denuded aorta. Data are shown as the mean ± SD and expressed as the percentage of the maximum contraction induced by isotonic 30 mM KCl. *P < 0.001 versus 10-9 M dexmedetomidine. Maximal contraction: †P < 0.001 versus no drug; ‡P < 0.001 versus 3 × 10-6 M rauwolscine.
