Table 1.
miRNAs predicted to regulate genes linked to MAM-induced DNA damage (O6-methylguanosine) in the brains of MAM-treated mice lacking the DNA-repair enzyme O6-methylguanine methyltransferase (based on data in Figure 3 of Kisby et al., 2011a).
| miRNA | Gene targets |
|---|---|
| miR-134 | Brain-derived neurotrophic factor (BDNF) and cAMP response element-binding factor (CREB) |
| miR-204 | BDNF and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) |
| miR-211 | BDNF and AMPA |
| miR-505 | BDNF and AMPA |
| miR-590-3p | BDNF and CREB |