Figure 1.

Detection of BrDU-positive cells by immunohistochemistry at different time points after PTA. (A) Three days after PTA, a few proliferating fibroblasts (brown cells) were positive for BrDU in the vascular adventitia; (B) 7 days after PTA, many BrDU-positive cells were noted in the adventitia and only a few BrDU-positive were noted in the media; (C) 14 days after PTA, the intima was thickened and the number of BrDU-positive cells increased and the nuclei of some cells were lightly stained; (D) 28 days after PTA, the thickening of the intima reduced and BrDU-positive cells were almost absent (magnification, x400).