Figure 2.
Transmission electron micrographs of hdp2; D53/+ IFMs to show age effects. (A-C) Transverse sections of IFM myofibrils (Myo) from 2- to 3-day-old flies: (A) Wild-type. (B) hdp2 showing the almost complete disruption of the myofibrils as a result of hypercontraction and (C) hdp2; D53/+ showing suppression but with some myofibrillar lattice disorder at the centers. (D, E) Transverse sections of myofibrils from 6- to 7-day-old flies: (D) hdp2; D53/+ flies demonstrating the increased central disruption of all myofibrils and (E) hdp2; D53/D53 myofibrils showing the complete suppression of hdp2 myofibrillar defects. (F) Longitudinal section of 6- to 7-day-old hdp2; D53/+ myofibrils, with disruptions at some of the Z-disk centers. Bar = 1 μm.
