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. 2001 May;12(5):1529–1539. doi: 10.1091/mbc.12.5.1529

Figure 5.

Figure 5

CLUSTALX multiple sequence alignment of muscle tropomyosin sequences corresponding to the TnT-2 binding site to show (a) position of S185F substitution in the protein sequence of the Drosophila Tm2 product expressed in the IFMs (TPM0_DROME); (b) consensus sequence (4 = KR, 6 = LIVM); (c) U = residues unique to the Tm2 product; (d) Heptad repeat ‘abcdefg ’ prediction generated with MacStripe (Dr. A. E. Knight, http://motility.york.ac.uk:85/) using the algorithm of Lupas et al. (1991). SwissProt Sequences: TPM0_DROME, Drosophila Tm2 gene product (P09491); TPM1 DROME, Drosophila Tm1 gene product (P06754); TPM1_HUMAN (P09493) and TPM3_HUMAN (P06753), human skeletal muscle α-chains; TPMA_BRARE (P13104), TPMA_COTJA (P18442), and TPMA_RABIT (P46902), zebrafish, quail, and rabbit skeletal/cardiac muscle α-chains; TPMA_RANTE (P13105), TPMA_RAT (P04692), TPMA_XENLA (Q01173), European common frog, rat, and South African claw toed frog skeletal muscle α-chains; TPMB_CHICK (P19352), TPMB_HUMAN (P07951), and TPMB_RABIT (P02560), chicken, human, and rabbit skeletal muscle β-chains; TPMC PIG (P42639), pig cardiac muscle α-chain; TPMM LOCMI (P31816) and TPMM_TRICO (P12324), locust and nematode muscle tropomyosins. Dots indicate residues identical to those in the TPM0 DROME sequence.