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The effect of naloxone or saline on PWLs in sham-operated rats tested 4 h, 7 days and 28 days after the injection of carrageenan. The data were obtained 10 min after intraperitoneal (i.p.) naloxone (n = 8) or saline (n = 8) and are presented for both the inflamed (A) and the contralateral non-inflamed (B) paws.▲P < 0.01, significantly different from PWLs before injection. *P < 0.01, significantly different between two groups of rats (Tsuruoka and Willis, 1996b).
