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. 2012 Sep 28;6:87. doi: 10.3389/fnint.2012.00087

Figure 5.

Figure 5

The stimulus–response relationship in wide-dynamic-range neurons located in the dorsal horn ipsilateral to the site of inflammation. (A) Stimulus–response relationship before the induction of inflammation. (B) Stimulus–response relationship at 4 h after the induction of inflammation. Closed circles (°) represent neurons in the LC/SC-intact rats (n = 11). Open circles (•) represent neurons in the LC/SC-lesioned rats (n = 20). Neuronal discharges to each temperature in graded heat stimuli (ordinate) are expressed as a percentage of the control. In (A) and (B), 100% (control) were discharges to heating at 53°C in the LC/SC-intact rats. #P < 0.05, ##P < 0.01, significantly different from the value of the LC/SC-intact rats (ANOVA, with Scheffe's t-test as a post hoc analysis of differences). *P < 0.05, significantly different between responses to heating at 49°C and responses to heating at 53°C (ANOVA, with Scheffe's t-test as a post hoc analysis of differences). (Tsuruoka et al., 2003).