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. 2012 Sep 28;6:87. doi: 10.3389/fnint.2012.00087

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Copyright © 2012 Tsuruoka, Tamaki, Maeda, Hayashi and Inoue.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

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Difference in inhibitory effect of LC/SC stimulation between the evoked discharge and the EMG activity. (A) Stimulation site of the LC/SC (closed circle). (B) The EMG activity in the masseter muscle evoked by an increase in the intensity in LC/SC stimulation. (C) An example of the effect of graded LC/SC stimulation on the evoked discharge and the EMG activity. Note that LC/SC stimulation at a stimulus intensity below 50 μA never produced EMG activity of the masseter muscle associated with stimulation of the mesencephalic trigeminal nucleus, located just lateral to the LC/SC, and that EMG activity was still observed even when the evoked discharge was completely inhibited by LC/SC stimulation at an intensity over 50 μA. Electrical stimulation of the descending colon is indicated by the arrow. (Tsuruoka et al., 2010b).