Figure 9.

The effect of either bilateral lesions of the LC/SC (A, n = 12) or sham lesions of the LC/SC (B, n = 10) on the tail flick latency. ^**P < 0.01, significantly different from the tail flick latency of the non-air-puff condition. Pre, pre-lesions; Post, post-lesions. Note that a significant Air-puff stimulation-induced prolongation of the tail flick latency was not observed in post-lesions of the LC/SC-lesioned rats, whereas tail flick latencies were significantly prolonged by air-puff stimulation in pre-lesions, suggesting that the descending inhibitory system from the LC/SC is involved in air-puff stimulation-induced antinociception (Tsuruoka et al., 2011).