Table 1.
Clinical features of normal controls and hepatitis C virus-infected patients (mean ± SD)
| Normal (n = 47) | HCV infection (n = 132) | P value | |
| Age (yr) | 50.51 ± 6.15 | 51.65 ± 5.50 | 0.24 |
| Gender (male/female) | 26/21 | 71/61 | 0.99 |
| Smoking (n) | 9 | 28 | 0.93 |
| Hypertension (n) | 1 | 30 | < 0.01 |
| Hyperlipidemia (n) | 4 | 21 | 0.31 |
| DM (n) | 0 | 35 | < 0.01 |
| WBC (103/mL) | 5.82 ± 1.48 | 5.75 ± 1.57 | 0.85 |
| Hb (g/dL) | 13.67 ± 1.77 | 14.49 ± 1.71 | 0.75 |
| Platelet (103/mL) | 251.24 ± 63.42 | 170.40 ± 58.00 | < 0.01 |
| AST (IU/L) | 23.19 ± 5.47 | 108.77 ± 60.73 | < 0.001 |
| ALT (IU/L) | 23.15 ± 9.45 | 168.69 ± 93.12 | < 0.001 |
| mtDNA | 247.93 ± 135.46 | 173.49 ± 147.40 | < 0.01 |
| mtDNA∆CT | 0.67 ± 0.48 | 2.92 ± 2.50 | < 0.01 |
HCV: Hepatitis C virus; ALT: Alanine aminotransferase; AST: Aspartate transaminase; DM: Diabetes mellitus; Hb: Hemoglobin; WBC: White blood cell; mtDNA: Mitochondrial DNA.