. 2012 Aug;60(8):567–575. doi: 10.1369/0022155412448070

Table 1.

Normalized Trastuzumab Binding Is Significantly Influenced by Pericellular Hyaluronan Density

Hyaluronan Density^a	Normalized Trastuzumab Binding^b	p Value^c
Low (730 ± 175)	2.13 ± 0.77	NA
Medium (1565 ± 340)	1.25 ± 0.59	0.001
High (2940 ± 295)	1 ± 0.35	0.001

Samples were divided into three groups based on their hyaluronan content according to the vertical reference lines in Figure 1A. Numbers represent the mean ± SD.

Normalized trastuzumab binding was calculated by taking the average of the pixelwise trastuzumab/OP15 intensity ratios. The numbers represent the mean ± SD.

p values of Tukey’s honestly significant difference test comparing the trastuzumab binding of the medium and high hyaluronan groups to that of the low hyaluronan group. NA, not applicable.