Table 1.

Summary of ¹H (700 MHz) and ¹³C (175 MHz) NMR Data for 2a in CDCl₃ and 3 and 4 in d₆-DMSO^a

		2a		3		4
positionb		δH (J in Hz)	δ C	δH (J in Hz)	δ C	δH (J in Hz)	δ C
Acyl	1		166.1, s		165.3, s		165.5, s
	2	6.98, 1H, d (16.0)	122.2, d	6.88, 1H, d (15.7)	123.3, d	6.71, 1H, d (15.7)	123.3, d
	3	7.91. 1H, d (16.0)	140.0, d	7.54, 1H, d (15.7)	137.1, d	7.55, 1H, d, 15.7)	137.0, d
	1′		133.6, s		138.0, s		138.0, s
	2′	7.56, 1H, d (7.80)	126.3, d	7.62, 1H, d (6.86)	125.9, d	7.58, 1H, d (7.63)	125.9, d
	3′	7.18, 1H, t, (7.60)	127.0, d	7.36, 1H, t (7.00)	129.0, d	7.37, 1H, t (7.21)	129.4, d
	4′	7.29, 1Hc	128.9, d	7.33, 1H, t (6.72)	127.4, d	7.33, 1H, t (7.35)	127.8, d
	5′	7.20, 1H, d (7.80)	129.9, d	7,19, 1He	129.7, d	7.20, 1Hf	130.5, d
	6′		138.4, s		137.0, s		137.0, s
	1″	6.55, 1H, d (11.4)	126.9, d	6.53, 1H, d (11.5)	126.9, d	6.51, 1H, d (10.8)	127.4, d
	2″	5.80, 1H, dt (11.5, 7.40)	134.9, d	5.79, 1H, m	134.1, d	5.78, 1H, m	134.1, d
	3″	2.00, 2H, m	30.5, t	1.97, 2H, m	30.0, t	1.98, 2H, m	29.0, t
	4″	1.35, 2H, m	22.7, t	1.36, 2H, m	22.1, t	1.36, 2H, m	22.9, t
	5″	0.80, 3H, t (7.50)	13.8, q	0.90, 3H, t (7.33)	13.6, q	0.81, 3H, t (7.28)	13.7, q
1Ser/1Thr	NH	7.65, 1H, d (7.80)		8.58, 1H, brs		8.64, 1H, brs
	α	5.45, 1H, m	50.9, d	5.01, 1H, m	52.9, d	5.05, 1H, m	51.3, d
	β	4.43, 1H, m	63.8, t	4.11, 1H, m	66.6, d	3.56, 1H, m	61.3, t
		4.68, 1H, m				3.80, 1H, m
	γ			1.05, 3H, brs	20.0, q
	CO		169.5, s		170.9, s		170.9, s
2ΔMeTyr	NMe	3.57, 3H, s	40.4, q	2.88, 3H, s	34.0, q	2.86. 3H, s	33.4, q
	α		138.8, s		130.7, s		129.4, s
	β	6.84, 1H, s	128.2, d	6.60, 1H, s	131.6, d	6.70, 1H, s	130.7, d
	1		131.0, s		123.5, s		123.3, s
	2,6	7.29, 2Hc	129.9, d	7.28, 2H, d (7.63)	129.3, d	7.19, 2Hf	130.7, d
	3,5	7.05, 2Hd	121.9, d	6.67, 2H, d (7.07)	115.1, d	6.67, 2H, d (7.98)	115.2, d
	4		150.9, s		158.4, s		158.6, s
	CO		166.0, s		164.9, s		165.3, s
	CO (Ac)		169.6, s
	Me (Ac)	2.30, 3H, s	21.1, q
3Leu	NH	8.08, 1H, d (8.20)		7.28, 1H, brs		7.35, 1H, d (9.35)
	α	4.45, 1H, m	51.1, d	4.35, 1H, m	51.5, d	4.39, 1H, m	51.5, d
	β	1.28, 1H, m	38.0, t	1.20, 2H, m	40.0, t	1.20, 2H, m	39.2, t
		1.64, 1H, m
	γ	1.00, 1H, m	24.2, d	1.15, 1H, m	23.9, d	0.85, 1H, m	24.0, d
	δ	0.71, 3H, d (6.60)	23.0, q	0.70, 3H, brs	21.7, q	0.73, 3H, d (6.20)	22.1, q
		0.79, 3H, d (7.10)	21.5, q	0.70, 3H, brs	22.7, q	0.73, 3H, d (6.20)	22.5, q
	CO		170.9, s		172.4, s		173.2, s
4Phe	NH	7.94, 1H, d (8.10)		8.49, 1H, brs		8.44, 1H, brs
	α	4.70, 1H, m	54.9, d	4.72, 1H, m	53.9, d	4.74, 1H, m	53.8, d
	β	2.79, 1H, m	36.7, t	2.71, 1H, m	38.0, t	2.72, 1H, m	37.4, t
		3.13, 1H, dd (13.8, 8.20)		3.05, 1H, m		3.05, 1H, m
	1		137.2, s		137.1, c		137.0, s
	2,6	7.12, 2H, d (7.50)	129.2, d	7.20, 2He	130.7, d	7.30, 2H, d (7.14)	129.7, d
	3,5	6.99, 2H, t (7.70)	128.4, d	7.22, 2He	127.8, d	7.22, 2Hf	129.0, d
	4	7.05, 1Hd	126.9, d	7.15, 1H, t (6.51)	126.0, d	7.14, 1H, t (7.28)	126.9, d
	CO		173.4, s		170.9, s		170.9, s
5allo Thr	NH	7.28, 1H, d (8.40)		8.10, 1H, brs		8.07, 1H, brd (6.23)
	α	4.93, 1H, dd (8.10, 3.60)	56.0, d	4.04, 1H, m	58.5, d	4.02, 1H, m	58.8, d
	β	5.28, 1H, m	69.1, d	3.65, 1H, m	67.0, d	3.68, 1H, m	67.6, d
	γ	1.18, 3H, d (6.60)	15.1, q	0.98, 3H, brs	20.0, q	0.97, 3H, brs	20.1, q
	CO		168.1, s		170.4, s		170.5, s
	CO (Ac)		170.5, s
	Me (Ac)	1.79, 3H, s	20.7, q
6Asn	NH	7.65, 1H, d (7.80)
	α	4.86, 1H, td (9.00, 4.40)	49.3, d
	β	2.63, 1H, dd (15.2, 4.30)	36.0, t
		2.81, 1H, m
	γCO		173.1, s
	CO		173.4, s
7Ser	NH	7.19, 1H, d (7.21)
	α	4.26, 1H, dd (11.3, 5.30)	52.7, d
	β	4.42, 1H, m	62.4, t
		4.58, 1H, dd (13.2, 7.70)
	CO		170.2, s
	CO (Ac)		170.9, s
	Me (Ac)	2.06, 3H, s	20.8, q

^aAssignments were based on COSY, HSQC, HMBC, and NOSEY experiments

^bNumbering followed literature precedence⁷

^cOverlapping signals

^dOverlapping signals

^eOverlapping signals

^fOverlapping signals