Table 2.
Variables | Categories | TCD abnormal | TCD normal | OR (95%CI) | p-value |
n(%) | n(%) | ||||
Gender | Male | 46 (54.1) | 366 (53.7) | 1.02 | 1.000 |
Female | 39 (45.9) | 315 (46.3) | (0.65-1.60) | ||
Genotype | SS | 82 (96.5) | 487 (71.5) | 10.88 | < 0.001* |
Others | 3 (3.5) | 194 (28.5) | (3.40-34.87) | ||
Complications of SCD | Yes | 42 (59.2) | 176 (31.3) | 3.18 | < 0.001* |
No | 29 (40.8) | 386 (68.7) | (1.92-5.27) | ||
Laboratory abnormalities | Yes | 24 (35.3) | 64 (11.8) | 4.09 | < 0.001* |
No | 44 (64.7) | 480 (88.2) | (2.33-7.17) | ||
Coexisting thalassemia | No | 82 (98.8) | 583 (92.7) | 6.45 | 0.032* |
Yes | 1 (1.2) | 46 (7.3) | (0.88-4.76) | ||
TCD method | Screening | 16 (18.8) | 47 (6.9) | 3.13 | 0.001* |
Routine | 69 (81.2) | 634 (93.1) | (1.68-5.81) |
SCD: Sickle cell disease: TCD: Transcranial Döppler ultrasonography: OR: Odds ratio; 95%CI: 95% confdence interval
*p-value < 0.05: Fisher Exact Test