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. 2012;34(4):307–310. doi: 10.5581/1516-8484.20120078

Table 2.

Distribution of clinical and laboratory characteristics of 773 patients with sickle cell disease according to transcranial Döppler ultrasonography

Variables Categories TCD abnormal TCD normal OR (95%CI) p-value

    n(%) n(%)    
Gender Male 46 (54.1) 366 (53.7) 1.02 1.000
Female 39 (45.9) 315 (46.3) (0.65-1.60)  

Genotype SS 82 (96.5) 487 (71.5) 10.88 < 0.001*
Others 3 (3.5) 194 (28.5) (3.40-34.87)  

Complications of SCD Yes 42 (59.2) 176 (31.3) 3.18 < 0.001*
No 29 (40.8) 386 (68.7) (1.92-5.27)  

Laboratory abnormalities Yes 24 (35.3) 64 (11.8) 4.09 < 0.001*
No 44 (64.7) 480 (88.2) (2.33-7.17)  

Coexisting thalassemia No 82 (98.8) 583 (92.7) 6.45 0.032*
Yes 1 (1.2) 46 (7.3) (0.88-4.76)  

TCD method Screening 16 (18.8) 47 (6.9) 3.13 0.001*
Routine 69 (81.2) 634 (93.1) (1.68-5.81)  

SCD: Sickle cell disease: TCD: Transcranial Döppler ultrasonography: OR: Odds ratio; 95%CI: 95% confdence interval

*p-value < 0.05: Fisher Exact Test