Table 5.
Negative predictive value (%) for three pairs of tests according to the parallel and serial testing schemes as well as epidemiological variables for donors with inconclusive serology screening
Parallel | Serial | |||||||||||
ELISA/c-ELISA | ELISA/rec-ELISA | c-ELISA/rec-ELISA | ELISA/c-ELISA | ELISA/rec-ELISA | c-ELISA/rec-ELISA | |||||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
General | 99.98 | 0.03 | 99.98 | 0.02 | 99.98 | 0.02 | 98.36 | 1.11 | 98.42 | 1.01 | 98.38 | 1.06 |
First time donor | 99.99 | 0.01 | 99.99 | 0.01 | 99.99 | 0.02 | 99.41 | 0.55 | 99.42 | 0.56 | 99.40 | 0.58 |
Repeat donor | 99.99 | 0.06 | 99.99 | 0.03 | 100 | 0.03 | 98.86 | 1.99 | 98.93 | 1.75 | 98.95 | 1.73 |
Age < 30 years | 99.63 | 0.58 | 99.67 | 0.43 | 99.66 | 0.45 | 89.82 | 5.67 | 90.17 | 5.42 | 90.01 | 5.45 |
Age > 30 years | 100 | 0.00 | 100 | 0.00 | 100 | 0.00 | 99.82 | 0.23 | 99.82 | 0.22 | 99.81 | 0.25 |
Male | 99.96 | 0.09 | 99.96 | 0.05 | 99.96 | 0.05 | 96.93 | 2.24 | 97.07 | 2.00 | 97.04 | 2.08 |
Female | 100 | 0.00 | 100 | 0.00 | 100 | 0.00 | 99.84 | 0.18 | 99.84 | 0.20 | 99.83 | 0.20 |
Endemic region | ||||||||||||
No | 99.93 | 0.10 | 99.94 | 0.08 | 99.94 | 0.08 | 97.11 | 1.70 | 97.19 | 1.65 | 97.20 | 1.50 |
Yes | 99.99 | 0.03 | 99.99 | 0.02 | 99.99 | 0.02 | 98.67 | 1.16 | 98.72 | 1.04 | 98.67 | 1.14 |
Contact with vector | ||||||||||||
No | 99.96 | 0.09 | 99.96 | 0.06 | 99.96 | 0.06 | 96.86 | 2.54 | 96.95 | 2.32 | 96.88 | 2.43 |
Yes | 100 | 0.00 | 100 | 0.00 | 100 | 0.00 | 99.82 | 0.19 | 99.83 | 0.18 | 99.82 | 0.19 |
Family history | ||||||||||||
No | 99.90 | 0.15 | 99.91 | 0.12 | 99.90 | 0.12 | 93.80 | 3.55 | 94.00 | 3.44 | 93.91 | 3.40 |
Yes | 100 | 0.01 | 100 | 0.00 | 100 | 0.00 | 99.77 | 0.33 | 99.78 | 0.27 | 99.77 | 0.33 |
SD: Standard Deviation