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EL overexpression promotes accumulation of TAG, LPC and LPE in mouse liver.
Perfused liver tissue was collected from fed, male C57Bl/6J mice, 24 h after i.v. injection of 3 × 109 virus particles of LacZ- or EL-Ad. The A) PC- B) PE- C) LPC- D) LPE- and E) TG-profile was determined in lipid extracts of 200 mg tissue. Results represent the mean ± SD of a representative experiment with 5 animals per group. Two additional experiments with 5 animals per group gave similar results.
