Skip to main content
. 2012 Jul 31;287(40):33142–33152. doi: 10.1074/jbc.M112.356782

FIGURE 1.

FIGURE 1.

Replisomes from HSV-1 and EHV-1 rely on species-specific interactions between subcomplexes for function. A, autoradiograph from a transient replication experiment using pORI(WT) and expression plasmids encoding replisome components from HSV-1 and EHV-1 as indicated. B, autoradiograph from a transient replication experiment using pORI(EHV-1) and expression plasmids encoding replisome components from HSV-1 and EHV-1. C, comparison of origin specificity for the HSV-1 and EHV-1 replisomes. The values are the ratio of the replication efficiency for the cognate origin versus the non-cognate origin determined from three independent experiments. A ratio of 1 indicates no discrimination between the origins of replication. Error bars, S.D.