TABLE 1.

Mutations in HSV-1 and EHV-1 UL8 exhibiting replication-defective phenotypes

The amino acid substitutions made in the various mutants are shown in boldface type (see also supplemental Table 1). Replication experiments are documented in Figs. 8 and 9. Replication efficiencies in the presence of the UL8 mutants were normalized to those obtained in the presence of either wt HSV-1 UL8 or WT EHV-1 UL8. The values are derived from duplicate experiments such as those described in the legends to Figs. 8 and 9.