FIGURE 5.
A, current recordings of a bilayer after fusion of a recombinant Oxa1 channel (membrane potential as indicated). Zoom plots show single gating events in main and subconductance states. B, conductance state histograms of Oxa1 at positive and negative applied holding potentials. C, conductance state histograms of Oxa1 at positive and negative applied holding potentials. Oxa1rec-containing proteoliposomes were incubated with Cox2 peptides prior to fusion. D, current recordings of a bilayer after fusion of an Oxa1rec-containing proteoliposome in the absence (left panel) and presence of 1 μm Cox IV1–23 (membrane potential of the voltage gate as indicated).