TABLE 5.

Characteristics of clusters of the ghrelin receptor models generated using Rosetta package

Rosetta score energy units are derived from empirical scoring function which has been shown to correlate to free energy.

Ghrelin receptor variant	Cluster no.	Cluster population	Rosetta score energy units
Wild type	1	2953	−576.213
	2	928	−573.512
	3	741	−567.742
	4	638	−571.403
	5	441	−555.434
	6	218	−568.565
	7	38	−561.738
	8	43	−553.315
A204E	1	4694	−574.853
	2	669	−572.966
	3	629	−589.463
	4	8	−552.394
A204K	1	3607	−571.082
	2	807	−575.319
	3	527	−571.934
	4	460	−567.033
	5	386	−565.036
	6	213	−570.042
G208A	1	2129	−573.486
	2	1533	−569.877
	3	645	−567.820
	4	536	−569.552
	5	288	−574.435
	6	281	−569.899
	7	226	−564.094
	8	220	−566.650
	9	142	−563.131