TABLE 3.

Kinetic constant for the inactivation of catBoNT/A catalytic domain by MTSEA and MTSPA

The experiments were performed in 40 mm Hepes, pH 7.4, at 37 °C, and the kinetic constants were determined from plots reported in Fig. 3.

Inhibitor	kinact	Ki	kinact/Ki
	s−1	μm	m−1·s−1
MTSEA	0.041	625	65
MTSPA	0.0034	7.7	440