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. 2012 Jul 18;287(40):33656–33663. doi: 10.1074/jbc.M112.375154

FIGURE 4.

FIGURE 4.

H37Rv induces significantly higher Th2 responses and the proinflammatory cytokine IL-1β compared with BCG or H37RvΔESAT-6. A, cytokine levels in lung homogenates of mice at different time points after infection with H37Rv or BCG. B, cytokine levels in lung homogenates of mice at different time points after infection with H37Rv or mutant strain H37RvΔESAT-6. Statistical significance between different strains was determined by one-way ANOVA: *, p < 0.01; **, p < 0.017; ***, p < 0.001. The results shown are representative of at least three independent experiments with six mice within each group. Error bars, ±S.D.