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C-10 Thioacetal Carbonates 11
| Compound | n | R | log P a | Yield |
|---|---|---|---|---|
| 11a | 3 | Me | 4.6 | 91% |
| 11b | 3 | n-Bu | 5.9 | 81% |
| 11c | 3 | t-Bu | 5.5 | 85% |
| 11d | 3 | PhF-4 | 6.4 | 77% |
| 11e | 3 | CH2C≡CH | 4.9 | 54% |
| 11f | 6 | Me | 5.9 | 82% |
| 11g | 6 | Et | 6.3 | 88% |
| 11h | 6 | CH2C≡CH | 6.1 | 64% |
| 11i | 6 | O(CH2)2S(O)2Ph | 6.6 | 63%b |
Log P values were calculated using ChemOffice® Ultra 11.0
This reaction was run in dichloromethane with pyridine as the base
