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Other Autoimmune and Inflammatory Conditions with Preclinical Evidence for PI3K Inhibition as a Potential Treatment
| Model | Isoforms Investigated and References |
|---|---|
| Passive cutaneous anaphylaxis | p110δ [82, 83], p110γ [58] |
| Asthma/airway inflammation | p110δ [78, 147, 175-178], p110γ [127, 179], dual p110δ and p110γ inhibition [180] |
| Experimental autoimmune encephalitis | p110δ [102] and p110γ [109, 122] |
| Atherosclerosis | p110γ [181] |
| Contact and delayed type hypersensitivity | p110δ [71], p110γ [59] |
