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. 2012 Sep 17;8:535–544. doi: 10.4137/EBO.S9976

Table 3.

Codon (amino acid) sites found to be under episodic diversifying selection.

Codon α β Pr[β = β] β+ Pr[β = β+] P-value q-value
3 0.71267 0 0.87743 33.051 0.12257 0.0357189 0.446487
26 0.594053 0.219727 0.83171 8.61427 0.16829 0.0427582 0.493364
48 0.592732 0.0233223 0.499489 7.0793 0.500511 0.0111048 0.23796
58 0.626032 0.153589 0.886189 208.891 0.113811 0.0471447 0.441982
64 0.578003 0 0.743857 3.43805 0.256143 0.0465647 0.465647
71 0.134445 0 0.846411 32.9029 0.153589 9.0959e-05 0.0136439
76 0.706383 0.043358 0.572077 7.49808 0.427923 0.0137215 0.257279
80 1.14485 0 0.823905 8.58932 0.176095 0.044903 0.481103
84 5e-09 5e-09 0.694404 8.03456 0.305596 0.000501674 0.0376255
95 5e-09 2. 5e-17 0.589632 3.53825 0.410368 0.0140873 0.234789
99 0.608495 0 0.854247 10.7894 0.145753 0.00485977 0.242988
107 0.320033 0.320033 0.938072 40.1285 0.061928 0.0289885 0.434828
110 0.330462 0.282797 0.966787 190.886 0.033213 0.0102668 0.25667
116 5e-09 2. 5e-17 0.725722 7.7696 0.274278 0.00678347 0.25438
126 0.934956 0.871756 0.913601 222.694 0.086399 0.0303443 0.413787
130 0.637836 0.00500758 0.600822 6.96584 0.399178 0.0100967 0.3029

Notes: Codon = codon (or amino acid) number in the alignment; alpha = the maximum likelihood estimate (MLE) of the synonymoys substitution rate alpha; β = the maximum likelihood estimate (MLE) of the non-synonymous rate for the branch class with β smaller or equal to alpha; Pr[ β = β] = the MLE of the proportion of sites evolving at β ; β+ = the MLE of the unconstrained β non-synonymous rate; Pr[ β = β+ ] = the MLE of the proportion of sites evolving at β+ ; P-value = the probability value for the likelihood ratio test statistic for β+ = alpha (null) versus β+ unrestricted (alternative); q-value = false discovery rate under the strict neutral null.