Table 1.

Pairwise divergence and nonsynonymous substitution ratios for mammalian DAZ family members

	hDAZL	cynDAZL	hDAZ	cynDAZ
mDAZL	10.4%*	11.0%*	16.1%†	15.8%†
	0.216	0.197	0.308	0.223
hDAZL	—	1.5%	9.1%†	9.6%†
		0.340	0.684	0.354
cynDAZL	—	—	10.9%†	9.5%†
			0.476	0.274
hDAZ	—	—	—	10.9%†
				0.530
mBOULE vs. hBOULE	8.3%‡	—	—	—
	0.128

The percentage number in each row is the uncorrected percent divergence in nucleotide sequence; the decimal number is the ratio of nonsynonymous substitutions per nonsynonymous site (K_a) to synonymous substitutions per synonymous site (K_a). Values were obtained using the gap and diverge programs of the GCG Wisconsin Package. m, mouse; h, human; cyn, cynomolgus monkey (Macaca fascicularis). GenBank accession nos. are U21663 (hDAZ), U65918 (hDAZL), U38690 (mDAZL), X99971 (cynDAZL), AJ012216 (cynDAZ), AF272858 (hBOULE), and AF272859 (mBOULE). 

^*Alignment omits last 4 codons of mDAZL and the stop codon of the primate DAZL. 

^† Based only on alignment of exons 1–7. 

^‡ Alignment omits last 8 codons.