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. 2012 Jun 22;12:17. doi: 10.1186/1472-6874-12-17

Table 2.

OR adjusted for Age and Study Population, stratified byHeight

SNP rs nr
Genotype
p-value for interaction
All individuals
Height <162.0 cm
Height 162.0-166.0 cm
Height >166.0 cm
 
 
 
case/contr: 2869/4480
case/control: 776/1366
case/control: 967/1407
case/control: 1023/1502
      OR 95%CI p-trend OR 95%CI p-trend OR 95%CI p-trend OR 95%CI p-trend
FGFR2 2981582
AA
 
1
 
1
 
1
 
1
 
 
Aa
 
1.23 (1.10-1.37)
 
1.35 (1.10-1.66)
 
1.33 (1.10-1.61)
 
1.07 (0.89-1.28)
 
 
aa
 
1.48 (1.29-1.69)
 
1.57 (1.21-2.02)
 
1.56 (1.22-1.99)
 
1.32 (1.04-1.67)
 
 
Per Allele
0,41
1.22 (1.14-1.30)
1.34E-08
1.26 (1.11-1.43)
2.86E-04
1.26 (1.12-1.42)
1.65E-04
1.14 (1.01-1.28)
0.03
TNR09 3803662
AA
 
1
 
1
 
1
 
1
 
 
Aa
 
1.14 (1.03-1.26)
 
1.09 (0.90-1.32)
 
1.23 (1.03-1.47)
 
1.15 (0.97-1.36)
 
 
aa
 
1.39 (1.17-1.67)
 
1.37 (1.00-1.87)
 
1.37 (1.00-1.89)
 
1.42 (1.03-1.95)
 
 
Per Allele
0,91
1.16 (1.08-1.25)
5.34E-05
1.14 (1.00-1.31)
0.06
1.20 (1.05-1.37)
6.78E-03
1.17 (1.03-1.33)
0.02
MAP3K1 889312
AA
 
1
 
1
 
1
 
1
 
 
Aa
 
1.21 (1.09-1.34)
 
1.29 (1.06-1.55)
 
1.14 (0.95-1.36)
 
1.18 (1.00-1.40)
 
 
aa
 
1.29 (1.09-1.54)
 
1.31 (0.95-1.81)
 
1.05 (0.76-1.45)
 
1.53 (1.14-2.06)
 
 
Per Allele
0,45
1.17 (1.08-1.26)
4.26E-05
1.20 (1.04-1.37)
9.92E-03
1.07 (0.94-1.22)
0.29
1.22 (1.07-1.38)
2.20E-03
8q24 13281615
AA
 
1
 
1
 
1
 
1
 
 
Aa
 
1.12 (1.00-1.24)
 
1.21 (0.98-1.48)
 
1.07 (0.89-1.29)
 
1.12 (0.93-1.34)
 
 
aa
 
1.15 (1.00-1.32)
 
1.24 (0.96-1.60)
 
1.17 (0.92-1.49)
 
1.09 (0.87-1.38)
 
 
Per Allele
0,90
1.08 (1.01-1.15)
0.03
1.12 (0.99-1.27)
0.07
1.08 (0.96-1.22)
0.20
1.06 (0.94-1.18)
0.35
LSP1 3817198
AA
 
1
 
1
 
1
 
1
 
 
Aa
 
1.12 (1.02-1.24)
 
1.19 (0.99-1.45)
 
1.08 (0.90-1.28)
 
1.08 (0.91-1.28)
 
 
aa
 
1.19 (1.00-1.40)
 
1.50 (1.11-2.02)
 
1.14 (0.84-1.55)
 
1.04 (0.79-1.38)
 
 
Per Allele
0,48
1.10 (1.02-1.18)
8.65E-03
1.21 (1.06-1.39)
4.41E-03
1.07 (0.94-1.22)
0.29
1.04 (0.92-1.18)
0.50
2q35
AA
 
1
 
1
 
1
 
1
 
 
Aa
 
1.05 (0.93-1.19)
 
0.90 (0.72-1.14)
 
1.21 (0.98-1.50)
 
0.97 (0.79-1.19)
 
 
aa
 
1.20 (1.05-1.37)
 
1.09 (0.85-1.40)
 
1.28 (1.01-1.63)
 
1.21 (0.96-1.52)
 
 
Per Allele
0,38
1.10 (1.03-1.17)
7.47E-03
1.05 (0.93-1.19)
0.43
1.13 (1.00-1.27)
0.04
1.10 (0.98-1.23)
0.11
ESR1 7766585
AA
 
1
 
1
 
1
 
1
 
 
Aa
 
1.23 (1.10-1.37)
 
1.12 (0.90-1.38)
 
1.26 (1.03-1.53)
 
1.25 (1.04-1.50)
 
 
aa
 
1.02 (0.74-1.41)
 
0.83 (0.43-1.58)
 
1.21 (0.69-2.13)
 
0.98 (0.57-1.66)
 
 
Per Allele
0,83
1.16 (1.05-1.27)
2.66E-03
1.05 (0.88-1.26)
0.60
1.20 (1.02-1.42)
0.03
1.16 (0.99-1.36)
0.06
HCN1 981782
AA
 
1
 
1
 
1
 
1
 
 
Aa
 
0.97 (0.87-1.09)
 
0.92 (0.74-1.14)
 
1.03 (0.84-1.26)
 
1.00 (0.82-1.21)
 
 
aa
 
0.86 (0.75-0.99)
 
0.91 (0.70-1.18)
 
0.96 (0.75-1.22)
 
0.77 (0.61-0.98)
 
 
Per Allele
0,51
0.93 (0.87-1.00)
0.04
0.95 (0.83-1.08)
0.44
0.98 (0.87-1.11)
0.73
0.88 (0.78-0.99)
0.04
ESR1 851987
AA
 
1
 
1
 
1
 
1
 
 
Aa
 
0.91 (0.82-1.02)
 
0.96 (0.78-1.17)
 
0.92 (0.76-1.11)
 
0.87 (0.73-1.05)
 
 
aa
 
0.88 (0.74-1.05)
 
1.44 (1.06-1.95)
 
0.69 (0.50-0.96)
 
0.71 (0.52-0.98)
 
  Per Allele 6.70E-03 0.93 (0.86-1.00) 0.06 1.12 (0.97-1.28) 0.12 0.86 (0.75-0.99) 0.04 0.86 (0.75-0.98) 0.02

None of the SNPs showed any tendencies towards significant interactions after stratification according to BMI (Table 3).