Table 1. Cellular localization of aquaporin-1 in the human and mouse trigeminal nervous system.
Regions | Neural elements | Humans | Mice |
Trigeminal ganglion | Medium and small-sized neurons | + | + |
Large-sized neurons | − | − | |
Satellite cells | + | + | |
Trigeminal peripheral root | Nerve fibers | + | + |
Trigeminal central root | Astrocytes | + | − |
Nerve fibers | − | + | |
Brain stem | Astrocytes | + | − |
Nerve fibers within spinal trigeminal tract and nucleus | − | + | |
Oral tissues | Mucosal and submucosal nerve fibers | + | + |
Subcutaneous and intramuscular nerve fibers | − | − |
+ represents AQP1 immunoreactivity is detectable and − represents is not.