Table 1. Relative IC50 values after treatment of human, chimpanzee and macaque cells with MMC.
Cell Line | Mean IC50 |
Human (AG13153) | 78.87 µM |
Chimpanzee (S006007) | 10.72 µM |
Macaque (AG07915) | 6.04 µM |
The differences in IC50 values between the human (AG13153) and chimpanzee (S006007) cells and between the human (AG13153) and macaque (AG07915) cells are significant (Student's t-test, p<0.05).