Figure 2. CpG ODN pre-treated cells increase cellular ODN uptake. RAW264.7 cells were pre-treated with either CpG ODN or GpC ODN for 30 min, followed by 0.5 μM GpC ODN-FITC or CpG ODN-FITC for 10 min. (A) The percentages of FITC-positive cells in total cells counted and (B) Cell fluorescence intensity of GpC ODN-FITC or CpG ODN-FITC uptake was measured by flow cytometry. Data represent the mean ± SD of 3 experiments. *p < 0.01 for CpG ODN pre-treated cells vs. GpC ODN pre-treated cells.