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. 2012 Sep 28;7(9):e46255. doi: 10.1371/journal.pone.0046255

Figure 5. EGFR immunohistochemical assay of the tumor sections from different groups.

Figure 5

A: 0 mg/kg As2O3 (control). The strongest red-brownish membrane-bound immunostaining on the A431 tumor tissue slice reflected the abundant over expression of EGFR (+++). B: 0.5 mg/kg As2O3 treatment group. Strong brownish membrane staining indicated plentiful of EGFR expression (++∼+++). C: 2.5 mg/kg As2O3 treatment group demonstrated moderate to low EGFR expression (+∼++). D: 5.0 mg/kg As2O3 treatment group showed weak EGFR expression (+). (Scale bar = 100 µm).