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. 2012 Sep 28;7(9):e46462. doi: 10.1371/journal.pone.0046462

Figure 7. The quorum sensing dependent regulation of Lcl plays a key-role in the control of L. pneumophila biofilm development.

Figure 7

Flow diagrams indicating the experimental stages when Las QS 3OC12-HSL auto-inducer (HSL) was used and the corresponding static biofilm assays (A). L. pneumophila strains Lp02, Lp02 pBH6119 (empty plasmid) and Lp02 Δlpg2644 plpg2644 were exposed to Las QS 3OC12-HSL during 48 h (B), the attachment phase (0–2 h) (C) and biofilm formation (2–48 h) (D). * P value <0.001 no HSL vs+HSL.