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WT (n = 21), HET (n = 22), and KO (n = 10) mice were tested in the spontaneous alternation test to assess their working memory. (A) The total number of arm entries was not affected by the genotype. (B) The percent of alternation in the Y-maze was significantly above chance level (50%) in WT and HET mice but not in KO mice. *** p<0.001.
