Figure 7. Sensori-motor gating assessed in the Npas4 line.

(A) During PPI testing, HET mice (n = 10) showed less inhibition than WT with a pre-pulse of 74 and 78 dB; KO mice (n = 6) showed less inhibition than WT (n = 5) for all pre-pulse intensities. (B) During the acoustic startle response trial, KO mice showed greater startle than HET at 100, 110, and 120 dB and than WT at 110 and 120 dB. *p<0.05; **p<0.01; ***p<0.001.