Table 3. Clinical features in Gambian children with severe malaria independently associated with a fatal outcome.

	Number of observations	Odds ratio	[95%CI]	P value	Sensitivity	Specificity	AUC (95%CI)
Impaired consciousness	2,885	4.4	2.7–7.3	<0.001	92.5	30.6	0.61 (0.59–0.63)
Respiratory distress	2,890	2.4	1.7–3.2	<0.001	63.0	63.2	0.63 (0.60–0.65)
Hypoglycemia	2,037	1.7	1.2–2.3	0.001	33.7	79.7	0.56 (0.53–0.59)
Jaundice	2,830	1.9	1.2–2.9	0.002	15.7	90.6	0.53 (0.51–0.55)
Renal failure	2,725	11.1	3.3–36.5	<0.001	3.1	99.6	0.51 (0.50–0.52)

The multiple logistic regression analysis included 1,931 observations with complete data (5 degrees of freedom) χ² = 180.4 (P<0.001); pseudo-R2 = 0.10; Goodness-of- fit, statistics: Hosmer-Lemeshow  = 4.47 (P = 0.61). AUC =  area under the curve.