Figure 5. Effect of LPA on COX-1 and COX-2 expression in the rat uterus during the window of implantation.

Uterine strips from rats pregnant on day 5 of gestation (implantation window) were incubated with LPA 50 µM for 6 h and the expression of COX-1 mRNA (A) and protein (B) and of COX-2 mRNA (C) and protein (D) was studied. In C: *** p<0,001 vs C; In D: ** p<0,01 vs C. Results are shown as means ± sem. N = 4–6 for each point. C: control.