Table 2. Twelve differentially expressed small RNAs each that are most over- or under-expressed in cases compared to controls.
| Mean Expression (sd)a | |||
| Cases (n = 22) | Controls (n = 23) | Fold-Change | |
| Overexpressed RNAs | |||
| miRPlus-E1016 | 211.82 (129.47) | 133.2 (53.13) | 1.59 |
| SNORD2 | 277.69 (156.92) | 185.25 (36.39) | 1.50 |
| SNORD44 | 132.65 (65.03) | 91.02 (17.84) | 1.46 |
| SNORD3@ | 602.26 (261.49) | 415.53 (104.4) | 1.45 |
| RNU5 | 750.37 (310.9) | 521.01 (111.97) | 1.44 |
| RNU6–1 | 552.41 (184.89) | 390.61 (118.08) | 1.41 |
| RNU6–1/RNU6–2 b | 4037.13 (1552.97) | 2878.75 (896.93) | 1.40 |
| miRPlus-C1110 | 312.42 (62.17) | 224.99 (50.54) | 1.39 |
| miRPlus-E1258 | 86.75 (20.49) | 64.07 (11.77) | 1.35 |
| miR-720 | 340.15 (119.55) | 252.95 (74.57) | 1.34 |
| miR-1290 | 171.55 (50.99) | 128.19 (32.76) | 1.34 |
| SNORD13 | 513.58 (204.28) | 384.05 (88.93) | 1.34 |
| Underexpressed RNAs | |||
| miR-144 | 143.57 (72.96) | 267.88 (119.29) | 0.54 |
| let-7f | 172.56 (96.41) | 312.48 (150.58) | 0.55 |
| miR-15a | 1067.1 (500.02) | 1899.57 (859.99) | 0.56 |
| miR-20a | 315.49 (215.14) | 560.07 (295.46) | 0.56 |
| miR-18a | 103.44 (62.86) | 175.58 (100.54) | 0.59 |
| miR-1976 | 1141.76 (601.13) | 1936.79 (853.76) | 0.59 |
| miR-93 | 585.97 (374.69) | 980.62 (477.89) | 0.60 |
| miR-20b | 50.43 (24.24) | 83.2 (43.62) | 0.61 |
| miR-320c | 207.32 (83.05) | 339.03 (172.55) | 0.61 |
| miR-17 | 604.37 (343.17) | 975.14 (443.34) | 0.62 |
| miR-652 | 126.41 (53.51) | 202.94 (75.64) | 0.62 |
| miR-18b | 44.08 (24.7) | 69.15 (38.45) | 0.64 |
a
Microarray signal values are shown.
b
Both RNU6-1 and RNU6-2 RNAs are detected by the same microarray probe.