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. 2012 Sep 28;7(9):e44196. doi: 10.1371/journal.pone.0044196

Table 1. Translocation datasets and permutation results.

Dataset Mean Hi-C Score (Translocations)* Mean Hi-C Score (Permutations)* Permutation P-Value Rank-Sum P-Value Individual Significant Translocations Total Unique Translocations % Genome Covered % Interactions Covered** Source
Mitelman Database 0.17±0.03 0.052±0.001 <0.001 6.42E-23 7 577 79.7% 1.12% Mitelman et al. 2011
Blood 0.19±0.03 0.063±0.001 <0.001 2.13E-20 6 440 72.4% 0.87%
Non-Blood 0.10±0.05 0.018±0.001 <0.001 1.78E-04 1 137 45.2% 0.27%
Multiple Myeloma 0.17±0.09 0.039±0.002 <0.001 7.27E-03 2 89 22.9% 0.03% Chapman et al. 2011
Prostate Cancer 0.07±0.04 0.002±0.001 <0.001 7.92E-04 0 89 21.9% 0.03% Berger et al. 2011
Mendelian 0.04±0.02 0.006±0.001 <0.001 4.05E-03 1 779 91.5% 0.79% https://www1.hgu.mrc.ac.uk/Softdata/Translocation/
*

Bounds represent a 95% confidence interval.

**

Percentage of inter-chromosomal 1-Mb bins that are covered by translocations.