Figure 6. Distinguishing features between the in silico strains.

A: GC content versus in silico growth rates. B: Growth rates in conditions, where the wildtype could not grow but biased strains and the metabolic model, iAF1260 [5], did. C: Changes of major leucine codon in the CUB perturbed ME-matrix. tRNA recognizing the codon is given in parenthesis. Leu1 and Leu2 are generic tRNA species representing multiple leucyl-tRNA species, see Table S2, and [23].