Skip to main content
. 2012 Sep 28;7(9):e44751. doi: 10.1371/journal.pone.0044751

Table 4. The most significant genomic regions under selection in MKK using XP-EHH, with LWK as the reference population.

Chr Start Position End Position Genes Number of SNPs Max XP-EHH
2 135058615 137017060 R3HDM1, MGAT5, RAB3GAP1, LCT, DARS, ZRANB3,MCM6, TMEM163, ACMSD, CCNT2, YSK4, UBXN4, CXCR4 572 12.182
5 14681797 14751400 FAM105B, ANKH 25 6.800
18 66712510 66731187 CCDC102B 12 5.587
5 115885282 115922669 SEMA6A 21 5.482
18 66768031 66777543 5 5.324
20 4513311 4522535 10 5.313
13 104870241 104880533 7 5.183
4 64594290 64639661 16 5.149
2 134507165 134561145 12 5.062
16 75360734 75364940 CFDP1 2 5.040
17 75427551 75428021 SEPT9 2 5.024
3 191943578 191989642 FGF12 10 5.019
11 117610387 117620420 DSCAML1 8 4.989

SNPs with positive genome-wide significant XP-EHH scores (XP-EHH ≥4.796, two-tailed Bonferroni corrected p≤0.05) were grouped into contiguous genomic clusters using genotype R2 using the same criterion as in Table 1. Overlapping clusters were merged. Column E lists the number of significant SNPs in each each cluster. Complete lists of genome-wide significant SNPs and clusters identified by XP-EHH are in Tables S3a and S3b.