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. 2012 Sep 28;7(9):e45802. doi: 10.1371/journal.pone.0045802

Figure 3. Predictions for independent Cohort III and Cohort IV samples.

Figure 3

The negative prediction rate for control cases is charted along with the positive prediction rates for cancer cases. PSA alone has high positive predictive rates for all cancer grades (>87%) but the combined PSA and RNA panel has lower positive prediction rates for the less aggressive G6 and G7(3+4) subgroups, 55%, and 49% respectively) while nearly the same positive prediction rate for the more aggressive G7(4+3) as G8 groups (79% and 83% respectively.