Table 4. Summary of validity and reliability measures for IsoScreen.

Analysis	Point estimate	95% Confidence Interval
Sensitivity (%)	93.2	80.3, 98.2
Specificity (%)	98.7	94.8, 99.8
Intra-rater variation, κ	0.75	0.48, 0.94
Inter-rater variation, κ	0.61	0.27, 0.90
Prevalence (%)	23.5	17.9, 30.1
Positive predictive value, PPV (%)	95.4	82.9, 99.2
Negative predictive value, NPV (%)	98.0	93.9, 99.5
Positive likelihood ratio, LR+	70.8	17.8, 281.2
Negative likelihood ratio, LR−	0.07	0.02, 0.2