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. 2012 Aug 30;107(7):1093–1099. doi: 10.1038/bjc.2012.368

Table 3. Summary of DLTs.

DLTs CTCAE grade Totala (%)
Increased ALT 3 3 (6)
Increased AST 3 3 (6)
Increased transaminasesb 3 2 (4)

Abbreviations: ALT=alanine aminotransferase; AST=aspartate aminotransferase; CTCAE=Common Terminology Criteria for Adverse Events; DLTs, dose-limiting toxicities.

a

A patient may have experienced more than one DLT.

b

Aminotransferases not specified.