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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: BJU Int. 2012 Jun 28;110(11C):E1138–E1146. doi: 10.1111/j.1464-410X.2012.11299.x

FIG. 3.

FIG. 3

Network analysis suggests an immune response and inflammation in ulcerative tissue and non-ulcerative tissue of patients with ulcerative interstitial cystitis (IC). Microarray data from patients with IC with Hunner’s ulcer (GSE11783) predict a hypothetical network, showing an immune response and inflammation signature (P < 0.01) in both ulcerative tissue and non-ulcerative tissue. The node and node boundary colours represent changes at the mRNA level in ulcerative tissue and non-ulcerative tissue of patients with IC, respectively, compared to tissue from healthy controls. The pathway information was obtained from the Kyoto Encyclopedia of Genes and Genomes pathway database.