Table 3.
eGFR ≥ 60 (ml/min/1.73 m2) (n = 14) |
eGFR < 60 (ml/min/1.73 m2) (n = 14) |
P value | |
---|---|---|---|
African American (%) | 55 | 44 | 0.6946 |
Diabetes mellitus (%) | 42 | 42 | 1 |
Age (years) | 62.57 ± 6.46 | 65.71 ± 8.49 | 0.1587 |
eGFR (ml/min/1.73 m2) | 85.97 ± 14.66 | 35.65 ± 6.4 | <0.0001 |
BMI (kg/m2) | 30.64 ± 5.54 | 28.88 ± 5.87 | 0.4229 |
Urine ACR (mg/g) | 0.13 ± 0.16 | 1.79 ± 2.37 | 0.0093 |
Serum FGF23 (pg/ml) | 80.92 ± 35.42 | 152 ± 34.81 | <0.0001 |
Serum 25(OH)D (ng/ml) | 11.6 ± 4 | 14.6 ± 5 | 0.0677 |
Serum 1,25(OH)2D (pg/ml) | 44 ± 19 | 43 ± 19 | 0.8329 |
Serum 24,25(OH)2D (ng/ml) | 1.24 ± 1 | 0.65 ± 0.5 | 0.0683 |
Serum PTH (pg/ml) | 58 ± 28 | 167 ± 117 | 0.0007 |
Serum alkaline phosphatase (IU/L) | 84.71 ± 25.71 | 95.57 ± 23.94 | 0.7304 |
Fractional excretion of calcium | 0.69 ± 0.65 | 1.15 ± 1.85 | 0.2140 |
Fractional excretion of PO4 | 12.26 ± 4.03 | 29.92 ± 8.63 | <0.0001 |
Categorical variables are presented as percentage and continuous variables as mean ± SD. Fisher’s exact test was used for the variable African American, Chi-square test for the variable DM. Unpaired t-test was used for the variables FGF-23, serum 25(OH)D, and BMI, Mann–Whitney U test was used for the rest of the continuous variables. eGFR, estimated glomerular filtration rate; BMI, body mass index; ACR, albumin creatinine ratio; FGF-23, fibroblast growth factor-23; 25(OH)D, 25-hydroxyvitamin D; 1,25(OH)2D, 1,25-dihydroxyvitamin D; 24,25(OH)2D, 24,25-dihydroxyvitamin D; PTH, parathyroid hormone, PO4; phosphorous.