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. Author manuscript; available in PMC: 2013 Oct 5.
Published in final edited form as: Vaccine. 2012 Sep 1;30(45):6359–6367. doi: 10.1016/j.vaccine.2012.08.051

Figure 5.

Figure 5

Humoral immunity at mucosal surfaces, the lung, following αDEC:LcrV immunization. (A) BALB/c mice were primed and boosted s.c. as shown at the left side of the graphs. Six to 10 days after the boost, anti-LcrV antibody titers for individual IgG isotypes and IgA in BAL fluid were determined by ELISA. Data are mean values from one of three similar experiments. (B-C) BALB/c mice were primed and boosted i.n. as described at the left. Six to 10 days after the boost, anti-LcrV antibody titers for individual IgG isotypes and IgA were measured in BAL fluid (B) (C), and in nasal washes and serum (C) by ELISA. Data shown are mean values from three similar experiments, using 3 mice per group. *p<0.05; **p<0.005; ***p<0.001