Table 1.
Abbreviations and explanations | |
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(i) AMPA: α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, GABA: γ-Aminobutyric acid (ii) EEG: Electroencephalogram (iii) CMRO2: Cerebral Metabolic Rate of Oxygen (iv) CPP: Cerebral Perfusion Pressure (v) ICP: Intracranial Pressure (vi) IV: Intravenous (vii) MAP: Mean Arterial Pressure (viii) t 1/2: Half-life (ix) Context sensitive t 1/2: the time taken for blood plasma concentration of a drug to decline by one half after an infusion designed to maintain a steady state (i.e., a constant plasma concentration) has been stopped. The “context” is the duration of infusion [5]. |