TABLE IV.

Published phage λ–host interactions^a

λ	Host	Description	References
Transcription
CI	RecA	RecA degrades CIb	Kobiler et al., 2004
CI	RpoA		Kędzierska et al., 2007
CI	RpoD		Li et al., 1994; Nickels et al., 2002
CII	ClpYQ	ClpYQ degrades CII in vitro	Kobiler et al., 2004
CII	ClpAP	ClpAP degrades CII in vitro	Kobiler et al., 2004
CII	HflD	HflD makes CII more vulnerable to FtsH (hfl, high-frequency lysogenization)	Kihara et al., 2001
CII	HflBc	HflB (= FtsH) protease degrades cII	Kobiler et al., 2002; Shotland et al., 2000
CII	RpoA		Kędzierska et al., 2004; Marr et al., 2004
CII	RpoD		Kędzierska et al., 2004
CIII	HflB	CIII inhibits HflB; HflB degrades CIII	Herman et al., 1997; Kornitzer et al., 1991
gpN	NusA	Transcriptional regulation	Friedman and Court, 2001
gpN	Lon	Lon degrades gpN	Kobiler et al., 2004; Gottesman et al., 1981
gpQ	σ70	gpQ makes RNAP insensitive to cis terminal	Marr et al., 2001;Nickels et al., 2002; Roberts and Roberts, 1996; Roberts et al., 1998
Head
gpB	GroE	genetic interaction; E. coli GroE	Ang et al., 2000; Georgopoulos et al., 1973; Murialdo, 1979
gpE	GroE	genetic interaction	Georgopoulos et al., 1973
Tail
gpJ	LamB	LamB is the E. coli receptor	Buchwald and Siminovitch, 1969; Clement et al., 1983; Mount et al., 1968; Wang et al., 2000a; Werts et al., 1994
Stf	OmpC	OmpC is a secondary E. coli receptor	Hendrix and Duda, 1992
Recombination
Xis	Lon	Xis is degraded by E. coli Lon protease	Leffers and Gottesman, 1998
Xis	FtsH	Xis is degraded by E. coli FtsH protease	Leffers and Gottesman, 1998
Xis	Fis	both required for excision	Ball and Johnson, 1991; Cho et al., 2002; Esposito and Gerard, 2003
Int	IHF	Both catalyze recombination at attP/attB	Campbell et al., 2002; Crisona et al., 1999
Gam	RecB	Gam inhibits RecBCD	Marsic et al., 1993
NinB	SSB	NinB also binds ssDNA	Maxwell et al., 2005
Replication
gpO	ClpXP	ClpXP degrades gpO	Kobiler et al., 2004
gpP	DnaA		Datta et al., 2005b,c
gpP	DnaB		Mallory et al., 1990

^aCbpA (Wegrzyn et al., 1996) perhaps interacts with DnaA and SeqA (Potrykus et al., 2002; Wegrzyn and Wegrzyn, 2001, 2002).

^bAfter DNA damage, RecA bound to single-stranded DNA stimulates autocleavage of the CI repressor (Kobiler et al., 2004).

^cHflB = FtsH.