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. Author manuscript; available in PMC: 2013 Sep 10.
Published in final edited form as: Biomacromolecules. 2012 Aug 21;13(9):2645–2654. doi: 10.1021/bm300472y

Figure 6. ELPAs (dpA3) and soluble ELPs (A192) both undergo LCST behavior.

Figure 6

The optical density was monitored over a temperature gradient of 1 °C per min from 45 to 80 °C. (a) A soluble ELP with a high MW (73.2 kD), A192 (100 μM=7.3 mg/ml). (b) ELPA nanofibers composed from the low molecular weight (1.7 kD) dpA3 (1000 μM=1.7mg/ml). (c) The transition temperatures for both constructs are inversely proportional to Log of concentration for both A192 (slope = -8.9 ± 0.8 °C (Log10[μM])-1 (mean ± 95% CI), r2 = 0.9975, p < 0.01) and dpA3 (slope = -7.1 ± 1.8 °C (Log10[μM])-1 (mean ± 95% CI), r2 = 0.98, p < 0.01).